Copyright©2018 CSIR-Institute of Genomics and Integrative Biology | VS Lab |
F-circEA | |||
Gene | EML4-ALK | Organism | Human |
Genome Locus | Exon4(EML4)-Exon22(ALK) | Build | hg19 |
Disease | Non-Small cell Lung Cancer tumorigenesis | ICD-10 | Malignant neoplasm of bronchus and lung (C34) |
DBLink | Link to database | PMID | 29628502 |
Experimental Method | |||
Sample Type | Tissues and Hep3B,Huh7 Cell lines | Comparison | H2228 or H1299 cells , non-small cell lung cancer patients versus control group |
Method for Estimation | Quantitative PCR | PCR Details | |
Primers (Experimented) | Forward CTGCAAGTGGCTGTGAAGA ReverseTCTGTGTATTTGGAGAGGTTGTG | Statistics | Fold Change : Upregulated pvalue : p<0.05 |
Citation | |||
Tan, S, Gou, Q, Pu, W, Guo, C, Yang, Y, Wu, K, Liu, Y, Liu, L, Wei, YQ, Peng, Y (2018). Circular RNA F-circEA produced from EML4-ALK fusion gene as a novel liquid biopsy biomarker for non-small cell lung cancer. Cell Res., 28, 6:693-695. |